Folic acid-targeted polydopamine-based surface modification of mesoporous silica nanoparticles as de

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：liongliong500

【摘要】

：

【作者】

：

Wei Cheng Teng Wang Chaoyu Liang Gan Liu Lin Mei Xiaowei Zeng

【机构】

：

Graduate School at Shenzhen,Tsinghua University,Shenzhen 518055,China

【出处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

drug delivery mesoporous silica nanoparticle polydopamine active targeting

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Mesoporous silica nanoparticles (MSNs),due to their excellent in vitro and in vivo biocompatibility and high drug loading capacity,have been used for drug delivery.In our previous work,a drug-loaded system of MSNs with surfaces modification of pH-sensitive polydopamine (PDA)for controlled drug release was prepared[1].

其他文献

Anticancer effects of cabazitaxel-loaded human serum albumin (HSA) nanoparticles

Taxanes have been used extensively for various types of cancer for nearly two decades[1].Cabazitaxel (Cbz),with antitumour activity in docetaxel-resistant cancers,belongs to the next generation of tax

会议

cabazitaxel_human serum albuminnanoparticlesa sustained releasesafety

VCAM-1 binding peptide conjugated DNA nanostructures for gene delivery to combat rheumatoid arthriti

Rheumatoid arthritis (RA) is a severe autoimmune disorder disease with chronic joint inflammation.NF-κB pathway is highly involved in the inflammation and can affect the secretion of various cytokines

会议

VCAM-1 binding peptideNF-kappa BNF-kappa B decoy oligodeoxynucleotidesrheumat

Esterase responsive charge-reversal vectors for gene delivery and therapy

Cationic polymers are widely used as nonvirial vectors to compact negatively charged DNA into DNA/polymer complexes (polyplexes)[1].However,the slow and incomplete release of DNA from the polyplexes i

会议

esterase responsiveDNA releasegene therapy

Poly(2-ethyl-2-oxazoline) conjugate of doxorubicin bound via pH-sensitive hydrazone linker:compariso

Polymer conjugates of doxorubicin (DOX) bound via hydrazone linker represent a very promising tool for cancer chemotherapy,as they offer triggered release of DOX in acidic conditions of tumor tissue a

会议

poly(2-oxazoline)poly(N-(2-hydroxypropyl)methacrylamide)drugdeliverydoxorubi

A novel injectable hydrogel system based on polyampholyte microgels

Hydrogels represent a promising technology platform for therapeutic intervention in a variety of diseases due to their capability of retaining water and other biomimetic properties[1].Among the varied

会议

injectable hydrogelspolyampholyte microgelspH-sensitivepoly(acrylic acid)pol

A nanoparticle with pH-triggered contrast amplification ability for tumor malignancy imaging

Accurate diagnosis of tumors and their pathological states could effectively improve the therapeutic outcomes.Magnetic resonance imaging (MRI) could provide high spatial resolution for imaging,and sev

会议

precision medicinepH-responsivecancer diagnosishypoxiametastasis

Ultra-small,glutathione responsive nanocaplets prepared via templated-polymerization for gene and pr

Advances in nanotechnology-based medicine offer excellent opportunity to design nanosized entities comprising pharmaceutical agents that can potentially track undruggable diseases (typically by small

会议

adhesive moleculetemplate polymerizationnanoparticlegene delivery

Gold nanoparticles coated by polyethylenimine-g-bovine serum albumin with different morphologies for

One of the biggest barriers for the further application of non-viral gene vectors is their unsatisfied gene transfection efficiency[1].Recent reports showed that the morphology of gene vectors influen

会议

gene deliverygold nanoparticlesmorphologycationized BSA

Targeting ROS-rich cancer cells with thermo/oxidation-responsive polymeric nanoaggregates:synthesis,

In human body,Reactive Oxygen Species (ROS) in inflammatory tissues are produced to play key roles in some physiological processes such as cell signalling and apoptosis,native immunity,and so forth[1]

会议

poly(propylene sulfide)stimuli-responsivenessdrug deliveryinflammation

The use of hydrophobic penetrating peptide cyclosporin A to deliver proapoptotic peptide:a possibly

A notable obstacle to develop peptide drugs is that native peptides often lack the capability to cross cell membranes and reach their intracellular targets.

会议

hydrophobic penetrating peptidecyclosporin Aproapoptotic peptideintracellular

Folic acid-targeted polydopamine-based surface modification of mesoporous silica nanoparticles as de

其他学术论文