IgY-loaded calcium phosphate nanospheres: preparation, sustained release and antibacterial activity

来源 :The Third Symposium on Innovative Polymers for Controlled De | 被引量 : 0次 | 上传用户：fntshb

【摘要】

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【作者】

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Xi Chen Feng Chen Xi-Ping Feng Ying-Jie Zhu

【机构】

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Department of Preventive Dentistry,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University S

【出处】

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The Third Symposium on Innovative Polymers for Controlled De

【发表日期】

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2014年6期

【关键词】

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calcium phosphate IgY sustained release antibacterial anti caries

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　　The exploration of safe and effective fluoride-free anti-caries materials has become an important field in the study of caries prevention.Ideal anti-caries material should possess such functions as antibacterial,re-mineralization and biocompatibility [1].In this study,novel IgY molecule loaded calcium phosphate (CaP) and lanthanum (La) doped CaP materials were designed as fluoride-free anti-caries materials.The CaP and La-Cap materials which were prepared with an amphiphilic polymer PLA-mPEG template were chosen as main constituents for IgY loading and release.Both the Cap and La-CaP materials exhibited nanospherical structures.

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IgY-loaded calcium phosphate nanospheres: preparation, sustained release and antibacterial activity

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