Selectivity comparison of cyclodextrin based capillary GC stationary phases

来源 :DaLian Internationall Symposia and Exhibition on Chromatogra | 被引量 : 0次 | 上传用户:chenfj01
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  One of the most important trends in chemical and biotechnology is an increasing demand for enantiomerically pure substances such as drugs, food additives, agrochemicals and reagents for research.The most versatile, convenient and accurate technique for the determination of the enantiomeric composition of volatile and semivolatile samples is chiral gas chromatography using capillary columns.High resolution, sensitivity and speed make chiral capillary gas chromatography ideal for the analysis of natural products and other complex mixes.The most versatile and popular commercial stationary phases are prepared using alpha, beta or gamma cyclodextrins that have been functionalized with various derivative groups at the 2, 3 and 6 positions on the sugar molecules.In this study we will compare and contrast the unique selectivity provided by cyclodextrins that have been derivatized with a variety functional groups such as trifluoroacetyl, permethyl, dimethyl, diacetyl and other unique derivatives.
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