Quinazolinones have emerged as new potential antimicrobial agents because of their broad spectrum of in vitro activity and their in vivo chemotherapeutic activity.
Nitrogen heteroarenes widely present in naturally occurring products and synthetic bioactive molecules,and as core structures of currently marketed drugs[1].
Nitrogen heteroarenes widely present in naturally occurring products and synthetic bioactive molecules,and as core structures of currently marketed drugs[1].
A series of novel 3-(2,4-dihydroxyphenyl)-propionic acid amides were synthesized and evaluated as tyrosinase inhibitors using a tyrosinase-dependent tyrosine oxidation assay.
Azole rings are an important class of unusual poly-nitrogen aromatic heterocycles able to readily interact with various biological cations,anions,small molecules and macromolecules such as DNAs,enzyme