Researches in the C-H Functionalizations of Heteroarenes

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：liongliong480

【摘要】

：

Nitrogen heteroarenes widely present in naturally occurring products and synthetic bioactive molecules,and as core structures of currently marketed drugs[1].

【作者】

：

Jing WEN Cheng-He ZHOU Gui-Xin CAI

【机构】

：

Key Laboratory of Applied Chemistry of Chongqing Municipality,Institute of Bioorganic & Medicinal Ch

【出处】

：

2015年全国药物化学学术会议暨第五届中英药物化学学术会议

【发表日期】

：

2015年3期

【关键词】

：

Heteroarene Benzimidazole Imidazole Triazole Thiazole

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Nitrogen heteroarenes widely present in naturally occurring products and synthetic bioactive molecules,and as core structures of currently marketed drugs[1].

其他文献

2-苄基-1-异喹啉酮类舒张血管活性的研究

：本研究组曾发现2-取代-3,4-二氢-1-异喹啉酮类和3-苄基-4-喹唑啉酮类化合物具有舒张血管的活性[1,2]。本课题合成了30 余种2-苄基-1-异喹啉酮类化合物,采用1H NMR 和HRMS表征目标化合物的结构。

会议

2-苄基-1-异喹啉酮合成抗高血压

Synthesis of Phosphonate Triazoles as New Type of Potential Antimicrobial Agents

Triazole drugs including Fluconazole,Itraconazole and Voriconazole have been prevalently used in the antiinfective therapy and also exhibit good anti-MRSA potency.

会议

PhosphonateTriazoleAntibacterialAntifungal

Synthesis of Conjugates of 5-Fluorouracil and Benzimidazole as Potential Anticancer Agents

5-Fluorouracil(5-FU)is a well-known antitumour agent widely used for the treatment of solid tumors.However,its clinical use is limited by many disadvantages such as short half-life,low selectivity,and

会议

5-FluorouracilBenzimidazoleSynthesisDNA

Synthesis and Antimicrobial Evaluation of Novel Sulfanilamide Nitroimidazoles

A series of novel sulfanilamide nitroimidazoles were synthesized via unique C-N cleavage of cyclic sulfanilamides by azole ring.Their structures were characterized by 1H NMR,13C NMR,IR,MS and HRMS spe

会议

SulfanilamideImidazoleAntibacterialSynthesis

Synthesis and Evaluation of Naphthalimides as Artificial Blocker for Bacterial DNA Replication

A series of Schiff base-appended naphthalimide derivatives were synthesized and characterized by NMR,IR,MS and HRMS spectroscopy.

会议

AntibacterialAntifungalSchiff baseNaphthalimide

Synthesis of Benzimidazole-based Fluconazole Analogues and Relational Antimicrobial Evaluation

Fluconazole is a well known first-line antifungal drug recommended by World Health Organization and is prevalently used to treat fungal infections by Candida albicans and Cryptococcus neoformans with

会议

BenzimidazoleFluconazoleAntibacterialAntifungal

A Green and Handy Approach toward Bioactive Benzimidazole Derivatives

Benzimidazoles are an important class of nitrogen-containing heterocycles,they display extensively potential applications as medicinal agents,supramolecular blocks as well as functional materials and

会议

Benzimidazoleβ-Amino carbonyl ingredientsAntibacterialAntifungal

Synthesis of Benzotriazolyl Chalcones as New Antimicrobial Agents

Chalcones bearing typical diaryl enone backbone are widely present in most natural fruits and vegetables,and have also been shown to display a diverse array of pharmacological activities,especially in

会议

ChalconeBenzotriazoleSynthesisAntibacterialAntifungal

Synthesis of Antimicrobial Coumarin-derived Azolyl Ethanols and Their Interactions with Calf Thymus

Coumarins have gained great therapeutic importance in the field of medicinal chemistry due to their extensively biological activities.

会议

CoumarinTriazoleAntibacterialAntifungalCalf thymus DNA

Novel Quinazolinones Containing Imidazole Acylhydrazone as Potential Antibacterial Agents

Quinazolinones have emerged as new potential antimicrobial agents because of their broad spectrum of in vitro activity and their in vivo chemotherapeutic activity.

会议

QuinazolinoneImidazoleAcylhydrazoneAntimicrobial

Researches in the C-H Functionalizations of Heteroarenes

其他学术论文