Drug-controlled release based on complementary base pairing rules for photodynamic-photothermal syne

来源 :第十一届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：leeannie222

【摘要】

：

Controlled drug release systems can enhance the safety and availability but avoid the side effect of drugs.Herein,we use the concept of DNA complementary base pairing rules in biology to design and pr

【作者】

：

Qi-chen Zhan Xian-qing Shi Jia-hong Zhou Lin Zhou Shao-hua Wei

【机构】

：

College of Chemistry and Materials Science,Jiangsu Key Laboratory of Bio-functional Materials,Jiangs

【出处】

：

第十一届全国化学生物学学术会议

【发表日期】

：

2019年3期

【关键词】

：

Drug delivery photothermal controlled drug release polydopamine complementary ba

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

基于ZnO纳米棒和纳米金的光电化学适配体传感检测Pb2+的研究

适配体(aptamer)是一种能够与相应的靶标物发生高亲和力和强特异性结合的DNA 或者RNA 片段，结合光电化学分析技术，以氧化铟锡(ITO)为基底电极，通过优化ZnO 纳米棒沉积参数及纳米金修饰方法，制备了光敏界面修饰的光电极(Au/ZnO/ITO)。

会议

适配体铅离子光电化学纳米金G-4联体

Chemical Intervention of ClpP:from antibiotic to antivirulence

Antibiotics has added an average of 20 years to our life.Unfortunately,bacteria are resistant to almost all antibiotics.

会议

SaClpPactivatorinhibitorantivirulenceantibiotic

Ratiometric Fluorescence Imaging of Endogenous H2Sn Revealing its Signaling Pathway in Non-Alcoholic

Hydrogen polysulfides(H2Sn,n > 1)proved to be a crucial reactive sulfur species(RSS)as their key functions in different biological processes were continuously revealed in recent years.

会议

H2Sn detectionprobe designratiometric fluorescence imagingsignal pathwayNAFL

Aromatic Rhodium complexes inhibit RNA demethylases

The exploration of RNA methylation was rejuvenated in the second decade of this century with the discovery of FTO as m6A demethylase in cells,which uncovered that RNA methylation is a dynamic and reve

会议

RNA demethylasesaromatic Rhodium complexesm6Alysosomes

定点磷酸化对于FUS淀粉样片段诱导其低复杂度区域从相分离到聚集的调控

FUS 是一种RNA 结合蛋白。它可以在细胞内形成功能性的无膜颗粒辅助RNA 行使功能，也会形成病理性聚集导致神经退行性疾病。细胞通过特定位点的丝氨酸/苏氨酸上的磷酸化来调控FUS 的组装形态，并抑制病理性聚集的产生。

会议

FUS聚集相分离磷酸化

Two-photon excited fluorescent probes using 1,5-diaminonaphthalene as reactive group for hypochlorit

Being one of reactive oxygen species,hypochlorite(-OCl)plays various roles in different psychological and pathological processes.

会议

fluorescent probehypochlorite15-diaminoanphthalenelysosomal

共生菌天然产物研究

会议

NMR Structural Basis for Higher-Order Human Telomeric G-quadruplex Complexes Induced by Platinum(Ⅱ)-

DNA guanine-rich sequences can form non-canonical secondary structures known as G-quadruplexes.It has been suggested that DNA G-quadruplexes are involved in several key biological processes and variou

会议

Platinum complexNMRG-quardruplexdynamic binding

Analysis of DNA assembly using solid-state nanopore

In recent years,solid-state nanopore analysis technology has begun to show increasing intersections with nucleic acid self-assembly research.

会议

Solid-state nanoporenucleic acid assemblyDNA nanotechnology

基于大环多胺[12]aneN3和三苯胺-咪唑酮(TPA-BI)作为具有双光子和AIE特性的非病毒基因载体

基因治疗是向病变细胞中导入正常基因以替换和修正病变基因，从而达到治疗的目的。由于磷酸基团的存在，核酸表面是带电负性的，同时，细胞表面有很多带负电荷的蛋白以及糖脂化合物，从而导致核酸很难直接通过胞吞作用进入细胞，因此，核酸能否顺利的进入细胞成为基因转染的难点。

会议

非病毒基因载体双光子荧光AIEDNA探针生物学跟踪

Drug-controlled release based on complementary base pairing rules for photodynamic-photothermal syne

其他学术论文