Advances in phosphodiesterase ( PDE) research:clinical potentials of PDE4 inhibitors in Alzheimer&#0 - 论文文献免费下载

Advances in phosphodiesterase ( PDE) research:clinical potentials of PDE4 inhibitors in Alzheimer�

来源 :中国药理学会第十三次全国学术大会 | 被引量 : 0次 | 上传用户：mantou119119

【摘要】

：

PDE is a superfamily of enzymes that break down the important second messengers cyclic AMP ( cAMP)and cyclic GMP ( cGMP) . There are 11 PDE families ( PDEl11); among them , PDE4 is the most important

【作者】

：

ZHANG Han-ting WU Qiang WANG Chuang HU Wei Rolf Hansen JIANG You-ming XU Ying James O'Donnell

【机构】

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Depts of Behavioral Medicine & Psychiatry and Physiology & Pharmacology,West Virginia University Hea

【出处】

：

中国药理学会第十三次全国学术大会

【发表日期】

：

2015年7期

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　　PDE is a superfamily of enzymes that break down the important second messengers cyclic AMP ( cAMP)and cyclic GMP ( cGMP) . There are 11 PDE families ( PDEl11); among them , PDE4 is the most important family in the control of intracellular cAMP sigmaling.

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Advances in phosphodiesterase ( PDE) research:clinical potentials of PDE4 inhibitors in Alzheimer�

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