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Exosomes ( EXs, 30~120 nm) and microvesicles ( MVs, 100~ 1000 nm) are two types of extracellularmicroparticles. Their contents (miRs and proteins) vary depending on cell origin and status. Mounting evidencesuggest that EXs and MVs mark the characters of their parent cells and represent a novel mechanism of intercellular communication.