【摘 要】
：
目的 评价对于术前下丘脑-垂体-肾上腺皮质功能正常的鞍区占位患者围手术期不应用糖皮质激素的安全性及对预后的影响.方法 纳入研究期间,本中心收治的影像学确认鞍区占位拟行
【出 处】
：
中华医学会2015全国神经肿瘤学术大会
论文部分内容阅读
目的 评价对于术前下丘脑-垂体-肾上腺皮质功能正常的鞍区占位患者围手术期不应用糖皮质激素的安全性及对预后的影响.方法 纳入研究期间,本中心收治的影像学确认鞍区占位拟行手术患者.根据患者的HPA 轴基础功能及储备功能评估结果,纳入HPA 轴功能正常的患者,随机分为试验组(不应用糖皮质激素组),及对照组(糖皮质激素快速减量组).入院后对患者进行全面的垂体功能评估.于术后及一年随访期中密切随访患者术后短期及中长期HPA 轴功能、术后并发症发生情况等.本随机对照临床试验通过本中心临床研究伦理委员会批准,并于ClinicalTrials.gov 通过注册认证(NCT02190994).采用Stata SE 12.1 统计软件包进行统计分析处理.
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