RIZ1a potential tumor suppressor in glioma

来源 :中华医学会2015全国神经肿瘤学术大会 | 被引量 : 0次 | 上传用户：morgan1912

【摘要】

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RT-PCR and western blot analysis showed that RIZ1 was downregulated in HGG compared with LGG and normal brain tissue.Immunohistochemistry showed less RIZ1 label

【作者】

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张晨冉 Hua He Qiubei Zhu Lei Jiang Xiaojun Wu Guohan Hu Xuehua Ding Liuhua Hu Yicheng Lu

【机构】

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第二军医大学附属长征医院神经外科第二军医大学附属长征医院耳鼻喉科上海仁济医院心内科

【出处】

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中华医学会2015全国神经肿瘤学术大会

【发表日期】

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2015年8期

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RT-PCR and western blot analysis showed that RIZ1 was downregulated in HGG compared with LGG and normal brain tissue.Immunohistochemistry showed less RIZ1 labeling in high-grade gliomas than in LGG.There was a negative correlation between RIZ1 and Ki-67 immunoreactivity.Clinicopathological evaluation revealed that RIZ1 expression was negatively correlated with tumor grade and patient age.

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RIZ1a potential tumor suppressor in glioma

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