【摘 要】
：
Infective endocarditis is an important illness with high morbidity and mortality.The prognosis is poor and has remained steady over the last 4 decades.The p
【机 构】
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Department of Cardiovascular Surgery Hospital Universitario La Princesa Universidad Autonoma de Madr
【出 处】
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BITs 2rd Annual World Cancer Congress of Cardiology-2010(201
论文部分内容阅读
Infective endocarditis is an important illness with high morbidity and mortality.The prognosis is poor and has remained steady over the last 4 decades.The pathogenic mechanism by which infection of the endocardium develops is multifactorial, depending upon factors associated with the local tissue microenvironment and the inoculated microorganisms.However, hereditary and immune factors may also contribute to its development.The Toll-like receptors (TLRs) are involved in the innate immune system.TLRs play a primary role in the innate immune recognition of invading microorganisms, initiating the adaptive immune response.
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