心肌营养素-1在冠心病患者行冠脉旁路移植术治疗前后的变化

来源 :第八届北京五洲国际心血管病会议 | 被引量 : 0次 | 上传用户:w13857464643
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  目的 观察冠心病(coronary heart disease,CHD)患者行冠状动脉旁路移植术(coronary artery bypass graft,CABG)治疗前后血清心肌营养素-1(cardiotrophin-1,CT-1)的变化及意义.方法 选择60例成功接受CABG的CHD患者,分别于术前、术后1d、1w测定血清CT-1浓度,于术前及术后1w行超声心动图(ultrasonic cardiogram,UCG)检查测定左心室射血分数(LVEF)、左心室舒张末期容积指数(LVEDVI)和左心室收缩末期容积指数(LVESVI).结果 ①CHD患者术后1d CT-1较术前增高(P<0.05);②CHD患者术后1w CT-1明显降低(P<0.05),且UCG各参数明显改善(P<0.05).结论 CHD患者血清CT-1升高,且CT-I与心功能关系密切,检测CT-1对CHD患者的治疗和心功能的评价有一定价值.
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