【摘 要】
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Objective To assess whether renal insufficiency is significant independent predictors of coronary artery disease.Methods We enrolled 1394 coronary artery disease patients undergoing coronary angiograp
【机 构】
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Depatment of Cardiolohy,Hebei 061500,China
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Objective To assess whether renal insufficiency is significant independent predictors of coronary artery disease.Methods We enrolled 1394 coronary artery disease patients undergoing coronary angiography procedures continuously from March, 2005 to March, 2011.Patients were classified as the level of glomerular filtration rate (eGFR).eGFR was calculated Estimated glomerular filtration rate (ml.min.1.73 m2) =186 × (Cr)-1.154 × (age)-0.203 × (0.742 if female)×(1.233 if Chinese).Depending on their baseline eGFR patients were classified into three groups: normalrenalfunction;mild renal impairment and severe renal insufficiency.We compared the clinical features and coronary artery lesions of patients.Results Significant differences were found among the groups regarding female gender, age, body mass index, prior history of hypertension, diabetes mellitus, prior stroke, heart failure, acute coronary syndrome, SBP, HbAlc, TG, TC, LDL-C (P<0.05) and risk of multivessel severe stenosis (P < 0.001).When evaluated as continuous variables, eGFR was independent predictors of coronary artery lesions (RR=2.33, 95%CI : 1.74~5.10).Conclusion Renal insufficiency and coronary artery lesion severity has close correlation.
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