Cycloaddition Reaction in Crystals: Reactivity Mediated by Noncovalent Interactions

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户:song52535
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  Controlled cycloaddition reactions mediated by noncovalent interactions have been applied in syntheses,especially in organic syntheses in solid state.Advantages of such reactions include high yield, convenient work up and "green" process.At first, we have demonstrated a copper-free 1,3-dipolar cycloaddition of azide and alkyne at room temperature in the solid state.[1] Crystal packing facilitated by arene-perfluoroarene interactions offered a desirable spatial arrangement of the azide and alkyne functional groups, and therefore promoted a relatively well-controlled regioselective "click" polymerization.
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