ELUCIDATION OF THE NONCOVALENT INTERACTION OF PC4 WITH TRANS-PTTZ DAMAGED DNA BY AMIDE HYDROGEN/EXCH

来源 :第十六届北京分析测试学术报告会 | 被引量 : 0次 | 上传用户:shibalian
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Our recent research has showed that the human nuclear protein positive cofactor PC4 selectively binds to transplatinated duplex DNA where the transplatinum complex trans-[PtCl2(NH3)(thiazole)](trans-PtTz) binds to guanine base to form 1,3-GTG intrastrand crosslink.
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