【摘 要】
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@@ Neuropathic pain is initiated by a lesion or dysfunction in the nervous system. It is associated with severe, chronic sensory disturbances characterized by spontaneous pain, enhanced responsiveness
【机 构】
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Department of Anesthesiology, Tianjin children's hospital
【出 处】
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天津医学会麻醉学分会2009年度学术年会
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@@ Neuropathic pain is initiated by a lesion or dysfunction in the nervous system. It is associated with severe, chronic sensory disturbances characterized by spontaneous pain, enhanced responsiveness to noxious stimulus (hyperalgesia), and pain in response to a normally nonnoxious stimulus (allodynia). Recently, however, the neuroimmune activation and neuroinflammation, which are indicated by the microglia and astrocytes hypertrophy and proliferation and the production of proinflammatory cytokines in the CNS, have been considered to play a major role in the development and maintenance of neuropathic pain[1].
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