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  5. Aberrant overexpression of CKIP-1 in osteoblast correlated with progressive bone erosion and decreas

Aberrant overexpression of CKIP-1 in osteoblast correlated with progressive bone erosion and decreas

来源 :第七届国际骨质疏松及骨矿盐疾病学术会议 | 被引量 : 0次 | 上传用户：khsim
【摘 要】
：
Background: CKIP-1 is an intracellular negative regulator for bone formation.However, its effect in failure of osteoblast-mediated repair for articular bone erosion in rheumatoid arthritis is still un
【作 者】
：
Xiaoiuan He Kang Zheng Yukun Zhao Baosheng Guo Jin Liu Ge Zhang Aiping Lu 
【机 构】
：
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Dongzhi
【出 处】
：
第七届国际骨质疏松及骨矿盐疾病学术会议
【发表日期】
：
2014年3期
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Background: CKIP-1 is an intracellular negative regulator for bone formation.However, its effect in failure of osteoblast-mediated repair for articular bone erosion in rheumatoid arthritis is still unknown.This study is to investigate the changes of CKIP-1 expression in osteoblast, bone erosion and bone formation in mice with collagen-induced arthritis.
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