The analysis of Shuanghuanglian injection by LCMS-IT-TOF

• 作 者: YueqiLi[1]HanminSong[2]FengyunPan[1]JingDong[1]JiaxiangHu[1]LeiCao[1]
• 机 构: Beijing Analytical Applications Center, Shimadzu International Trading(Shanghai) Co., Limited, Beiji
• 出 处: 第2届大连国际色谱学术报告会、第37届国际高效液相色谱及相关技术会议、第18届全国色谱学术报告会
• 发表日期: 2011年期

　　Shuanghuanglian injection is a traditional Chinese medicine extracted and purified from honeysuckle (double flowers), skullcap and forsythia.As the composition of shuanghuanglian injection is complex and diverse, a comprehensive study of its chemical composition is very difficult.A method was development for rapid determination of chemical composition in Shuanghuanglian injection on UFLC coupled with LCMS-IT-TOF.Identified 20 kinds of main components by precise molecular weight and MSn fragment, and analyzed the possible fragmentation pathway and structures of these compounds.