The anti-mitogenic effect of sorafenib and meformin on human anaplastic thyroid carcinoma cells

来源 :中华医学会第十二次全国内分泌学学术会议 | 被引量 : 0次 | 上传用户：leonontop

【摘要】

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【作者】

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Guofang Chen Xiaodong Mao Shuhang Xu Chao Liu

【机构】

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Endocrine and Diabetes Center,Jiangsu Province Hospital on Integration of Chinese and Western Medici

【出处】

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中华医学会第十二次全国内分泌学学术会议

【发表日期】

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2013年7期

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Objective Metformin, a classical and safe anti-diabetic agent, was demonstrated to exert anti-mitogenic effect on anaplastic thyroid carcinoma (ATC) cells and amplify the anti-mitogenic effect of chemotherapeutic agents as doxorubicin and cisplatin.The multi-kinase inhibitor sorafenib is a promising option for treating aggressive and resistant cancer including anaplasticthyroid carcinoma.

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The anti-mitogenic effect of sorafenib and meformin on human anaplastic thyroid carcinoma cells

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