【摘 要】
：
Uridine-disphosphate glucuronosyltransferase 1A1 (UGT1A1) enzyme,one of the most important class of Phase Ⅱ conjugative enzymes, involved in essential elimination and detoxification of a host of poten
【机 构】
：
Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Acade
【出 处】
：
2015年第一届药代动力学朝阳论坛
论文部分内容阅读
Uridine-disphosphate glucuronosyltransferase 1A1 (UGT1A1) enzyme,one of the most important class of Phase Ⅱ conjugative enzymes, involved in essential elimination and detoxification of a host of potentially harmful compounds, including both the xenobiotics (e.g., SN-38, etoposide and diethylstilbestrol) and endogenous compounds (e.g., bilirubin, β-estradiol, bile acids, and inflammatory mediators).
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