【摘 要】
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A phase Ⅱ, randomized study suggests that recombinant human endostatin(endostar)plus dacarbazine can yield a significant improvement in PFS and OS.Intratumoral Microphthalmia-associated transcription
【机 构】
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Department of Renal cancer and Melanoma, Peking University School of Oncology,Beijing Cancer Hospita
【出 处】
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第十六届全国临床肿瘤学大会暨2013年CSCO学术年会
论文部分内容阅读
A phase Ⅱ, randomized study suggests that recombinant human endostatin(endostar)plus dacarbazine can yield a significant improvement in PFS and OS.Intratumoral Microphthalmia-associated transcription factor(MITF)might be a predictive biomarker of this regimen because of upregulation of hypoxia-inducible factor 1α, which contributes to angiogenesis and disease progression.melanoma patients.
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