Exposure to maternal Diabetes causes renal Dopamine D1 receptor dysfunction and hypertension in adul

来源 :Ready for 2018- the 4th China International Forum on Hyperte | 被引量 : 0次 | 上传用户：playallprogram

【摘要】

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Objective:Epidemiological and experimental studies suggest that maternal diabetes programs adult hypertension in the offspring, but the underlying mechanisms are incompletely understood.Here, we test

【作者】

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Hao Luo Shuo Chen Xinquan Wang Jialiang Wang Caiyu Chen Xiaolong Li Chunyu Zeng

【机构】

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The Department of Cardiology,Daping Hospital,The Third Military Medical University,Chongqing,P.R.Chi

【出处】

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Ready for 2018- the 4th China International Forum on Hyperte

【发表日期】

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2015年3期

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Objective:Epidemiological and experimental studies suggest that maternal diabetes programs adult hypertension in the offspring, but the underlying mechanisms are incompletely understood.Here, we test the hypothesis that in utero exposure to maternal diabetes impairs renal D1 receptor function in adulthood offspring, and oxidative stress plays a central role in this phenomenon.

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Exposure to maternal Diabetes causes renal Dopamine D1 receptor dysfunction and hypertension in adul

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