The neuroprotective effects of HOEC against hydrogen peroxide-induced cytotoxicity and apoptosis via

来源 :第八届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：dongshantongak

【摘要】

：

Oxidative stress plays an important role in the pathological processes of various neurodegenerative diseases, such as Alzheimers disease (AD).(+)-2-(1-hydroxyl-

【作者】

：

Jiao-Ning Shen Rui Wang

【机构】

：

DepartmentofPharmaceuticalSciences,SchoolofPharmacy,ShanghaiKeyLaboratoryofNewDrugDesign,EastChinaUn

【出处】

：

第八届全国化学生物学学术会议

【发表日期】

：

2013年9期

【关键词】

：

Oxidative stress Neuroprotection Hydrogen peroxide SH-SY5Y cells MAPK

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Oxidative stress plays an important role in the pathological processes of various neurodegenerative diseases, such as Alzheimers disease (AD).(+)-2-(1-hydroxyl-4-oxocyclohexyl) ethyl caffeate (HOEC), a caffeic ester, was isolated as a major constituent from lncarvillea mairei var.granditlora (Wehrhahn) Grierson.

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The neuroprotective effects of HOEC against hydrogen peroxide-induced cytotoxicity and apoptosis via

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