Yangjing CaPsule Extract Promotes Proliferation of GC-1 SPg Cells via UP-regulated POU3F1 Pathway

• 作 者: BinCai[1]BaofangJin[1]XindongZhang[2]YueguiCui[3]DalinSun[1]BinChen[1]GuanghuiChen(MM)[1]YongWang(MM)[4]ChaoGao(MM)[3]
• 机 构: Andrology DePartment of Integrative Medicine, Zhongda HosPital, Southeast University, Nanjing210009,
• 出 处: 首届全国不孕不育复发性流产中西医诊治暨生殖健康高峰论坛、第五次全国中医生殖医学学术研讨会、2015中华中医药学会生殖医学
• 发表日期: 2015年期

　　Background: As similar to glial cell line-derived neurotroPhic factor (GDNF),the Yangjing CaPsule (YC) extract could also lead to Proliferation of sPermatogonial stem cells (SSCs) by motivating PhosPhoinositide 3-kinase (PI3K)/Protein kinase B (AKT)Pathway; however, the regulatory effect of YC extract on the exPression of POU3F1 still remains unknown.