【摘 要】
：
In the recrystallized agglomeration process the drug crystals in their good solvents are transformed directly in to compacted agglomerated forms during the
【机 构】
：
KIMS University Krishna Institute of Pharmacy,Karad India
【出 处】
：
中国上海第七届国际新药发明科技年会
论文部分内容阅读
In the recrystallized agglomeration process the drug crystals in their good solvents are transformed directly in to compacted agglomerated forms during the recrystallization process in their poor solvent.It also enables co-precipitation of drug and encapsulating polymers in the form of spherical agglomerates.This technique of particle design of drug substances has emerged as one of the areas of active research currently of interest in pharmaceutical manufacturing and recently came into the forefiront of interest due to the fact that crystal habit can be modified during the crystallization process.In consequence of such modifications in the crystal habit certain micrometric properties and physicochemical properties can also be modified due to the polymorphic changes during recrystallization.
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