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By using an integrated approach of experiment, CALPHAD (CALculation of PHAse Diagrams) and first principles calculations, new thermodynamic and thermophysical databases including diffusivity, volume, viscosity, and thermal conductivity databases for multicomponent Al alloys have been developed in our research group.All the databases were critically validated by comprehensively comparing the calculated and the measured quantities in sub-binary, ternary and even commercial Al alloys.