A new 20-membered macrolide produced by a marine-derived Micromonospora strain

• 作 者: PengFei[1]LianYun-yang[2]WangChuan-xi[1]XieYang[1]JiangHong-lei[1]ChenLu-iie[1]PaulinaUribe[3]AlanT.Bull[4]MichaelGoodfellow[5]JiangHong[1]
• 机 构: Fujian Key Laboratory of Screening for Novel Microbial Products, Fujian Institute of Microbiology, F
• 出 处: 第四届全国微生物资源学术暨国家微生物资源平台运行服务研讨会
• 发表日期: 2012年期

　　A new 20-membered macrolide named as levantilide C was isolated from the Micromonospora strain FIM07-0019 recovered from shallow coastal waters near the island of Chiloe,Chile.The chemical structure of levantilide C was elucidated on the basis of one-and twodimensional NMR analysis.Two known indole derivatives were also isolated from this strain.Levantilide C exhibited moderate antiproliferative activity against several tumor cell lines.