MOLECULAR AND PHARMACOLOGICAL C HARACTERIZATION OF A NOVEL SEROTONIN RECEPTOR FROM THE CATERPILLAR,

来源 :The 10th Conference of Insect Physiology, Biochemistry and M | 被引量 : 0次 | 上传用户:littlewolfwolfwolf
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  The biogenic amine serotonin (5-hydroxytryptamine, 5-HT) is an important neurotransmitter in both vertebrates and invertebrates.It plays a key role in the regulation of many physiological and behavioural processes through distinct G protein-coupled receptors.Until now, insect is known to express four 5-HT receptor subtypes that are predicted to be orthologs of the mammalian 5-HT1A, 5-HT1B, 5-HT2, and 5-HT7 receptors.We have isolated a cDNA (Pr5-ht8) from the caterpillar: Pieris rapae, which shares relatively low similarity to the known serotonin receptor families.
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