Low expression LncRNA RPLPOP2 is associated with poor prognosis and decrease cell proliferation and

• 作 者: 王瑜敏
• 机 构: 温州医科大学附属第一医院
• 出 处: 浙江省免疫学会第十次学术大会
• 发表日期: 2016年8期
• 关键词: lung adenocarcinomas lncRNAs RPLPOP2 LRRC10B gene function

　　Objective:We aimed to unveil the clinical roles and biological function of lncRNA RPLPOP2 in lung adenocarcinoma (LAD).Materials and methods:The expression level of RPLPOP2 was estimated by qPCR in 57 pairs of LAD and NT samples and the relation of RPLPOP2 to clinical data of LAD patients was analyzed.We overexpressed RPLPOP2 basing on human LAD cell line A549 by lentivirus-mediated technology,then observed oncology behavior change of A549 cells and the change of mRNA level of LRRC10B and RPLPOP2 by qPCR.