Multifunctional binary-drug loaded liposomes for targeting cancer therapy

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户:yqy1980
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Nanocarriers have shown great potential for targeting delivery of therapeutic molecules to tumors[1].Compared to small molecule anti-cancer drugs,nanomedicines with the features of tumor targeting,long blood circulating time,high drug accumulation in tumor tissues,and low toxicity to normal tissues are a more promising therapeutics in cancer treatment[2].
其他文献
Nanoscale drug delivery systems could endow the antitumor agents with passive and active targeting ability[1].However,these nanomedicines developed to date mainly transport drugs to the cytoplasm rath
Metal organic framework (MOF) nanomaterials (e.g.,zeolitic imidazolate framework,ZIF) have shown great promise in the field of biomedical applications,in particular as a nanocarrier for drug delivery[
Gene therapy has been explored as a treatment strategy for diverse disease.Various gene carrier systems including viral,non-viral,and their hybrid vectors have been studied for efficient gene delivery
Vitamins are well-known anti-oxidants for elimination of reactive oxygen species (ROS) and have been used for enhanced cell survival in ROS-induced diseases and cell damages.[1]Some hydrophilic vitami
Low therapeutic efficacy in conventional drug delivery systems is usually attributed to the inadequate cellular uptake and/or the improper efflux of drug molecules[1].Wherein,the plasma membrane as a
Fluorescent conjugated polymer nanoparticles have wide applications in display device,bioimaging and sensing due to their superior fluorescence properties.Latent fingerprints (LFP) have been particula
Efficient delivery of proteins and peptides into cells remains a major challenge due to the presence of multiple barriers in intracellular protein delivery.In recent years,functional nanoparticles hav
Nanoscale stimuli-responsive systems for gene and drug delivery have recently received tremendous attention[1].The systems that sensitive to a specific trigger may provide a specific release of the pa
Over the past decades,much effort has been devoted to design of novel sustained/controlled drug delivery systems.However,as commonly used fluorescent components,organic dyes usually suffer from rapid
Adjuvant chemotherapy is the most important strategy to prevent the recurrence of bladder cancer after surgery[1].However,the low permeability effect and short residence time of intravesical drug make