• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Seven novel PHEX gene mutations in Chinese subjects with X-linked hypophosphatemic rickets/osteomala

Seven novel PHEX gene mutations in Chinese subjects with X-linked hypophosphatemic rickets/osteomala

来源 :第七届国际骨质疏松及骨矿盐疾病学术会议 | 被引量 : 0次 | 上传用户：bhf0520
【摘 要】
：
Background: X-linked hypophosphatemic rickets/osteomalacia (XLH;OMIM307800), the most frequent form of inherited rickets in human, is a dominant disorder of phosphate homeostasis resulting in defectiv
【作 者】
：
Shanshan Li Zhenlin Zhang 
【机 构】
：
Metabolic Bone Disease and Genetic Research Unit, Department of Osteoporosis and Bone Diseases, Shan
【出 处】
：
第七届国际骨质疏松及骨矿盐疾病学术会议
【发表日期】
：
2014年3期
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background: X-linked hypophosphatemic rickets/osteomalacia (XLH;OMIM307800), the most frequent form of inherited rickets in human, is a dominant disorder of phosphate homeostasis resulting in defective bone mineralization.
其他文献
Leonurine hydrochloride inhibits osteoclastogenesis and prevents estrogen deficiency-induced osteopo
Background: Osteoclasts, the primary bone-resorbing cells, are responsible for bone destructive diseases such as postmenopausal osteoporosis, rheumatoid arthritis, and periodontitis.Many plant-derived
会议
Histomorphometry analyses: Preclinical and clinical application
Bone histology and histomorphometry have played essential role in the study of bone pathphysiology and are important in the diagnosis and management of metabolic bone diseases.In osteoporosis research
会议
骨质疏松症合并糖尿病患者血清AGE水平与骨胶原改变的相关性研究
目的 通过比较单纯骨质疏松与合并糖尿病患者在血清胶原代谢指标、骨中胶原成熟度、交联成分变化以及羟基磷灰石结晶度等指标的差异,探索血清胶原代谢指标与骨基质胶原代谢指标的相关性.
会议
The association between SOST gene polymorphisms and bone response to alendronate in Chinese postmeno
Background: Sclerostin (SOST) is an important antagonist for Wnt pathway of osteoclast.We investigate the association between SOST gene polymorphisms and bone response to alendronate (ALN) treatment i
会议
Correlation of esRAGE with bone strength,bone mineral density and bone metabolism in postmenopausal
Background: To investigate whether the serum endogenous secretory receptor for advanced glycation end products (esRAGE) was correlated with bone strength, bone mineral density and bone metabolism in p
会议
The BMD both in cortical and trabecular lumbar vertebrae decreased significantly in Chinese patients
Background: To assess the changes of bone mineral density (BMD) in patients with ankylosing spondylitis (AS) by QCT and guide the clinical treatment.Methods: The BMD of lumbar vertebra 1-5 were measur
会议
Bone mineral density, spinal micro-architecture (tbs data) and body composition in the older Ukraini
Background: Osteoporosis and sarcopenia are the most frequent musculoskeletal disorders affecting older people.Fracture incidence as well as the number of fractures increase due to the population s ag
会议
Early regional adaptation of bone mineral density after anterior cruciate ligament reconstruction
Background: The aim of the study was to analyze the adaptation of bone mineral destiny (BMD) and its influence on cartilage damage after anterior cruciate ligament (ACL) reconstruction in a combined r
会议
Regional features of bone mineral density in women kuzbass (Western Siberia, Russia)
Background: In the diagnosis of osteoporosis is important dual-energy X-ray absorptiometry (DXA).During DXA bone mineral density of the patient compared with the reference database that was originally
会议
MicroRNA-34c在间充质干细胞自发成骨分化过程中的作用机制研究
目的 检测在人骨髓间充质干细胞(MSC)自发成骨分化过程中miR-34c的表达变化及其启动子区甲基化程度的变化,探索miR-34c在MSC自发成骨分化过程中的作用及调控机制.方法 通过多次传代构建老化MSC模型,通过对硝基苯酚法、放射免疫法及Western blot检测在MSC自发老化的过程中ALP活性、OC分泌以及Runx2蛋白的表达变化,以明确在MSC老化过程中其成骨能力的改变;用qRT-PC
会议