Detection of miR-224 in serum of primary hepatocellular carcinoma patients and its clinical signific

• 作 者: Xiaodong Guo Mei Yang Hongping Zhang Jingrnin Zhao Shuhong Liu Yulai Zhao Liyuan Wu Chaonan Guo
• 机 构: 302 Military Hospital of China, Beijing
• 出 处: 第四届国际人体微生态大会、第十三届中华预防医学会微生态学学术会议、第五届中国医师协会感染科医师大会暨传染病诊治高峰论坛、
• 发表日期: 2013年5期

　　Objective To investigates the expression of miR-2242 in serum of primary hepatocellular carcinoma(PHC)patients,as well as their clinical significance.Methods The blood samples were collected from 40 patients with PHC,20 patients with chronic hepatitis,20 patients with chronic hepatic cirrhosis and 20 normal subjects.The expression levels of miR-224in the serum were measured by reverse transcription polymerase chain reaction.Pearsons correlation analysis was used to estimate the relationship between miRNA expression and traumatic injury.The correlations of miR-224 expression to the prognosis were analyzed.