【摘 要】
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Aims: to assess the association between maternal gene polymorphisms of the enzymes involved in Folate metabolism and the risk of having a DOWN Syndrome (DS)
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Aims: to assess the association between maternal gene polymorphisms of the enzymes involved in Folate metabolism and the risk of having a DOWN Syndrome (DS)offspring in southern China mothers.Methods :Four gene polymorphisms of three key enzymes in Folate metabolizing were analayzed in 84 southern china mothers with a DS children (MDS,the case group);and 120 control mothers (age-matched,the control group).
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