Mycoplasma ovipneumoniae induces sheep airway epithelial cell apoptosis by increasing production of

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户:xiaofengwuxuan123
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Mycoplasma ovipneumoniae (M.ovipneumoniae) is a species of Mycoplasma bacteria that specifically infects sheep and goat, which is the cause of ovine infectious pleuropneumonia.In an effort to understand the pathogen-host interaction between the M.ovipneumoniae and airway epithelial cells, we investigated the host cell apoptosis in a primary air-liquid interface (ALI) epithelial culture model generated from bronchial epithelial cells of Ningxia Tan sheep (ovis aries).We found that M.ovipneumoniae initially bound to ciliated epithelial ceils of the sheep bronchial epithelial cell ALI cultures.
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