Involvement of NF-kB in Connective Tissue Growth Factor-Induced Cyclooxygenase-2 (COX-2) Expression

来源 :2011年第一届内分泌与代谢大会 | 被引量 : 0次 | 上传用户：sunxunjun2008

【摘要】

：

【作者】

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Chia-Wei Liang Bing-Chang Chen Chien-Huang Lin

【机构】

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Graduate Institute of Medical Sciences College of Medicine Taipei Medical University Taiwan

【出处】

：

2011年第一届内分泌与代谢大会

【发表日期】

：

2011年3期

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　　In traumatic process of central nervous system (CNS), connective tissue growth factor (CTGF) regulates a wide range of cellar process, including angiogenesis and reactive gliosis.There is growing evidence that increased expression of cyclooxygenase-2 (COX-2) in acute CNS injury.However, the molecular mechanisms underlying CTGF-induced COX-2 expression are still undefined.In this study, we investigated the involvement of IκB kinase (IKK) and NFκB in CTGF-induced COX-2 expression in C6 glioma cells.

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Involvement of NF-kB in Connective Tissue Growth Factor-Induced Cyclooxygenase-2 (COX-2) Expression

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