Effect of Junctional Adhesion Molecule-2 (JAM-2) Expression on Cell Growth, Invasion and Migration i

来源 :首都医科大学第三届研究生学术论坛 | 被引量 : 0次 | 上传用户：asdfasdf32111

【摘要】

：

　　Background: The junctional adhesion molecule (JAMs) family belongs to the immunoglobulin subfamily involved in the formation of Tight Junctions (TJ) in both

【作者】

：

HuishanZhao[1]HefenYu[2]TraceyA.Martin[3]YuxiangZhang[2]GangChen[2]WenG.Jiang[4]

【机构】

：

Department of Biochemistry and Molecular Biology, School of Basic Medicine,Capital Medical Universit

【出处】

：

首都医科大学第三届研究生学术论坛

【发表日期】

：

2015年期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Background: The junctional adhesion molecule (JAMs) family belongs to the immunoglobulin subfamily involved in the formation of Tight Junctions (TJ) in both endothelial and epithelial cells.Aberrant expression of JAM-2 is associated with cancer progression but little work has been carried out in discovering how this affects changes cell behaviour.

其他文献

Inhition of 1,4-Benzoquinone-lnduced Apoptosis by Downregulating miR-34a Expression

　　Growing evidence shows that miRNAs are altered after exposuring to environmental toxicants.It has recently been found that significant alteration of miRNAs

会议

Clinical and Genetic Characteristics of DICER1 Syndrome: a Systematic Review

　　It has been previously reported that heterozygous germline DICER1 mutations correlated with a distinctive human disease syndrome involving pleuropulmonary b

会议

Cross Talk Between Poly(ADP-ribose) Polymerase 1 Methylation and Oxidative Stress Involved in the To

　　Given the tremendous growth in the application of titanium dioxide nanoparticles(TNPs), concerns about the potential health hazards of TNPs to humans have b

会议

Cannabinoid Receptor 1 But not 2 Mediates Macrophage Phagocytosis by G(α)i/o/RhoA/ROCK Signaling Pat

　　Phagocytosis is critical to macrophages linking innate and adaptive immune reaction.Cannabinoid receptor 1 (CB1) and 2 (CB2) mediate immune modulation.Howev

会议

c-kit信号在结直肠黏液性腺癌发生发展中的作用机制研究

　　结直肠癌是目前危害人类健康较为常见的恶性肿瘤之一；其发病率和致死率分别位居所有恶性肿瘤的第三位和第四位。结直肠黏液性腺癌(colorectal mucinous adenocarcinoma,CR

会议

c-kit信号结直肠腺癌黏液性发生发展恶性肿瘤肿瘤恶性程度转移能力

6-OHDA大鼠棕色脂肪的变化及对体温和脂肪代谢的影响

　　以中枢黑质多巴胺能神经元缺失和体重减轻为主要病理特征的帕金森病(Parkinson's disease,PD)的发病率和患病率逐年上升,已成为严重影响人类健康的重要疾病之一。探索影

会议

分泌蛋白Fstl1在乳腺癌脑转移中的作用及其机制研究

　　乳腺癌脑转移是乳腺癌致死的主要原因之一,探寻这一过程的关键因子是预防及治疗乳腺癌脑转移的关键.FSTL1在多种肿瘤中表达异常,与多种乳腺癌脑转移相关蛋白存在相互作用

会议

The Expression of NHERF1 Associated with Hypoxic Microenvironment and VEGF/VEGFR Signaling Activatio

　　Background: Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) is a scaffold protein with 358 amino acids.It is known to interact with a number of cancer-rel

会议

15-Deoxy-△12,14-prostaglandin J2抑制单核巨噬细胞中巨噬细胞移动抑制因子表达的机制研究

　　目的探讨15-Deoxy-△12,14-prostaglandin J2(15d-PGJ2)对小鼠单核巨噬细胞中巨噬细胞移动抑制因子(macrophage migration inhibitory factor, MIF)表达的调节及机制.方

会议

多巴胺受体在人胰腺中的定位

　　多巴胺主要通过其五种受体(D1DR-D5DR)发挥作用，它可以调节胰岛素的分泌，临床上已有多巴胺受体的激动剂被用来治疗二型糖尿病，但机制并不清楚。已有研究报道小鼠、大鼠和人

会议

Effect of Junctional Adhesion Molecule-2 (JAM-2) Expression on Cell Growth, Invasion and Migration i

其他学术论文