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  5. Development of rotigotine loaded PLGA implants to achieve CDS for the treatment of PD

Development of rotigotine loaded PLGA implants to achieve CDS for the treatment of PD

来源 :2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 | 被引量 : 0次 | 上传用户：lfwvb
【摘 要】
：
Continuous dopaminergic stimulation (CDS) has become the focus of the treatment strategy for Parkinsons disease (PD) that can prevent the development of dyskinesia[1].However, the currently available
【作 者】
：
Jingyao Gan Aiping Wang Yanxiang Liu Youxin Li Kaoxiang Sun Wanhui Liu 
【机 构】
：
School of Pharmacy, Yantai University, Yantai, China, 264005
【出 处】
：
2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会
【发表日期】
：
2015年9期
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Continuous dopaminergic stimulation (CDS) has become the focus of the treatment strategy for Parkinsons disease (PD) that can prevent the development of dyskinesia[1].However, the currently available CDS treatment options, such as duodenal infusion of L-DOPA(Duodopa(R)) and rotigotine transdermal delivery system (Neupro(R)), are associated with disadvantages of poor compliance, high cost or varied efficacy [2,3].
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