妊娠期糖尿病患者体液1H NMR代谢轮廓分析

来源 :第十八届全国波谱学学术年会 | 被引量 : 0次 | 上传用户：y58141917

【摘要】

：

妊娠期糖尿病(GDM)是妊娠期常见的并发症之一,对母婴的危害极大[1].GDM的病理机制尚未清楚,其早期诊断方法也不成熟.基于NMR的代谢组学研究机体内源性小分子代谢物的组成随疾病发生和发展的变化规律,为GDM的研究提供全新理念.本文采用1HNMR技术对GDM和健康妊娠志愿者的血清和尿液的代谢轮廓进行分析,并结合多元统计建模方法分析GDM的特征代谢物,探索GDM的受损代谢通路.

【作者】

：

周玲 Cheng Kian-Kai 沈桂平许晶晶董继扬陈忠

【机构】

：

厦门大学电子科学系,厦门 361005 Department of Bioprocess Engi

【出处】

：

第十八届全国波谱学学术年会

【发表日期】

：

2014年4期

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