Huaier suppresses proliferation and induces apoptosis in human pulmonary cancer cells via promotion

• 作 者: TangweiWu[1]ZhongxinLu[2]WeiqunChen[2]ShuiyiLiu[3]HongdaLu[4]HuiWang[5]DeyongKong[5]XiaodongHuang[6]QinzhiKong[7]YongNing[8]
• 机 构: Department of Medical Laboratory,Central Hospital of Wuhan,Wuhan 430014,China
• 出 处: 中国病理生理学会第十四届肿瘤专业委员会、第十五届免疫专业委员会联合学术会议
• 发表日期: 2014年期

　　Aqueous extract of Trametes robiniophila murr(Huaier)has been applied for cancer complementary therapy in recent decades.Varies studies have reported that Huaier possess the anti-tumor effects.However,the mechanisms are not completely elucidated.MicroRNAs (miRNAs) are small (18-25 nucleotides),noncoding RNAs whose dysregulation have been discovered to involve in tumorigenesis and development.In this study,we found miRNA expression profiles were altered in Huaier-treated human pulmonary adenocarcinoma A549 cells.