miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation

• 作 者: Zhenhua Li
• 机 构: 军事医学科学院生物工程研究所
• 出 处: 2016第四届“模式生物与人类健康”发育遗传学峰会
• 发表日期: 2016年4期

Basal autophagy is tightly regulated by transcriptional and epigenetic factors to maintain cellular homeostasis.Dysregulation of cardiac autophagy is associated with heart diseases,including cardiac hypertrophy,but the mechanism governing cardiac autophagy is rarely identified.