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肿瘤多药耐药(MDR)是指肿瘤细胞对一种药物出现耐药性后，对其他化学结构和作用机制不同的药物产生交叉耐药性[1]。肿瘤的多药耐药形成机制有多种，其中研究最深入也是最重要的一种机制为ABC(ATP-Binding Cassette)超家族膜蛋白介导的药物外排泵的过表达。
甲基化(+)-儿茶素及其衍生物的合成
【摘 要】
：
肿瘤多药耐药(MDR)是指肿瘤细胞对一种药物出现耐药性后，对其他化学结构和作用机制不同的药物产生交叉耐药性[1]。肿瘤的多药耐药形成机制有多种，其中研究最深入也是最重要的一种机制为ABC(ATP-Binding Cassette)超家族膜蛋白介导的药物外排泵的过表达。
【机 构】
：
中国海洋大学海洋药物教育部重点实验室;山东省糖科学与糖工程重点实验室,山东青岛266003 香港理
【出 处】
：
全国药物化学学术会议暨第四届中英药物化学学术会议
【发表日期】
：
2013年11期
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