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目的 WehypothesizedthatNETswereproducedinaVILImodelandmaycontributetoinjury.方法 InVILImousemodelwithandwithoutintratrachealDNasetreatment,weassessedmarkersoflunginjuryandinflammation.NETswereassessedbyimmunofluorescencemicroscopy,BALFlevelofMPO-DNAcomplexes,citrullinated-histoneH3andextracellularDNA.