Continuous flow synthesis of substituted benzobisimidazoles - precursors for cruziforms

来源 :The 14th International Conference on Microreactivity Technol | 被引量 : 0次 | 上传用户:kevinlynx
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  So-called "Cruciforms" are aromatic fluorophores consisting of two perpendicular conjugated π-systems,which form a cross-like structure.They are commonly used as fluorencent materials for optoelectronics.1,2 The central aromatic core of theses substances often consists of condensed heteroaromatics,such as benzobisimidazoles.3 Using flow chemistry,we highly increased the productivity,selectivity and convenience of the underlying synthetic strategies.The original batch synthesis of these heterocycles involves a series of inconvenient,dangerous,and unselective reactions,ranging from nitrations to substrates with multiple functional groups with little to no difference in reactivity.
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