The Role of the Immune System in the Dynamics of Chronic Myeloid Leukemia

来源 :第八届工业与应用数学国际大会 | 被引量 : 0次 | 上传用户：zhwa

【摘要】

：

　　We develop a mathematical model of chronic myeloid leukemia(CML)and the immune system,and apply it to patient data collected throughout therapy.Many patient

【作者】

：

ClappGeoffrey;

【机构】

：

Univ.of Maryland,College Park

【出处】

：

第八届工业与应用数学国际大会

【发表日期】

：

2015年期

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　　We develop a mathematical model of chronic myeloid leukemia(CML)and the immune system,and apply it to patient data collected throughout therapy.Many patients who respond well to therapy exhibit a biphasic exponential decline in cancer load,followed by a period of damped oscillations.Our data and modeling results suggest that a patient's immune system plays a significant role in these dynamics and that the oscillations may represent an immune response to CML.

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The Role of the Immune System in the Dynamics of Chronic Myeloid Leukemia

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