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To date,there are few researches on capacitive micromachined ultrasonic transducer (CMUT) to measure the ultra-low pressure.The graphene-based CMUT was proposed for the measurement of the ultra-low pressure.The array cavities were etched on a silicon substrate,and a single-layer graphene membrane was transferred directly to be attached on the substrate to cover the cavities,then the CMUT was fabricated.We employed the finite element method (FEM) simulation to investigate the sensing performance of this new CMUT structure.The measuring sensitivity of the graphene-based CMUT was analyzed with the value of 20.34 kHz/Pa,which was nearly 600 times higher than that of the silicon membrane based CMUT (30 Hz/Pa).The results showed that the proposed graphene-based CMUT has good linearity and high sensitivity for the ultra-low pressure detection.