Copper is vital to cell function.The influx of reduced copper ions is controlled by homologous transmembrane solute carrier transporter CTR1 (encoded by SLC
Accumulating evidence has revealed that brain iron concentrations increase with aging, and the choroid plexus may be at the basis of iron-mediated toxicity
Maternal copper deficiency in mammals is known to severely restrict offspring growth and development.Accordingly, the maternal dietary requirements for copp
Iron is an essential metal involved in many fundamental biochemical processes within a living cell or organism.In mammals, ceruloplasmin and hephaestin, two
There are two general forms of sideroblastic anemia, namely congenital sideroblastic anemia (CSA) and acquired sideroblastic anemia.The CSAs are a group of
Frataxin (FXN) is a mitochondrial protein that is involved in mitochondrial iron homeostasis and iron-sulfur cluster biogenesis.Defective expression of FXN
Porphyrias are a group of rare inherited or acquired disorders caused by deficiencies in the activities of the enzymes involved in heme biosynthesis pathway
Two homogeneous pectins with different structure, LJW2F1 and LJW2F2 were isolated from flowers of Lonicera japonica Thunb.and their sulfated derivatives were pr