Identification and Characterization of the major histocompatibility complex class II DQB (MhcMath-DQ

• 作 者: YongfangYao[1]JingjingZhao[2]YantingWang[3]LiangZhou[4]QingyongNi[1]HuailiangXu[1]
• 机 构: College of Animal Science and Technology,Sichuan Agricultural University,Ya'an,625014
• 出 处: 第八届全国野生动物生态与资源保护学术研讨会
• 发表日期: 2012年期

　　Tibetan macaque( Macaca thibetana),an endangered primate species endemic to China,have been used as experimental animal model for various human diseases.To gain an insight into the MHC background and to facilitate the experimental use of Tibetan macaques,the second exon of Mhc-DQBl genes was sequenced in a cohort of wild Tibetan macaques living in the southwest of China.A total of 22 MhcMath-DQBl alleles were identified for the first time,illustrating a marked allelic polymorphism at the DQBllocus for these macaques.