Relationship between the expression of IP-10,IP-10 mRNA in peripheral blood and the level of HBV-DNA

来源 :2008病毒性肝炎成就与挑战国际研讨会(International Confernece on Viral Hepati | 被引量 : 0次 | 上传用户:balonbalon
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Objective:To study the relationship between the expression of IP-10, IP-10 mRNA in peripheral blood and the level of HBV-DNA in serum of patients with cirrhosis.Methods The typical patients with cirrhosis after HBV infection were selected, and their serum IP-10 concentrations were evaluated with ELISA, the content of IP-10 mRNA in peripheral blood mononuclear cells (PBMCs) was measured by Real-time PCR.The level of IP-10 mRNA was represented by Ig cDNA/Ig GAPDH.
其他文献
会议
会议
会议
BACKGROUND: YIC (HBsAg complexed with anti-HBs) has been shown to revert immune tolerance in a transgenic mouse model.In phase Ⅰ and Ⅱ clinical trials, YIC induced high titer of anti-HBs in healthy ad
会议
HBV deletion mutants complicate the progression of viral liver diseases.This study analyzed HBV sequences from 103 patients including 51 whole genomes and 70 preS clones.Among three hotspots we observ
会议
The tumor necrosis factor (TNF)-related apoptosis-inducing ligand(TRAIL) has recently been implicated in the death of hepatocytes during HBV infection, but the molecular mechanisms are not well unders
会议
Nosiheptide is a drug with good anti-HBV activity but poor liver delivery due to its high liposolubility and low hepatocellular selectivity.In this study, high-density lipoprotein (HDL) was used as th
HCV affects 170 million people, but there are no vaccines in routine clinical use.Development of effective vaccine against HCV that elicit robust long-term T cellular immune response is required to pr
会议
Human hepatitis B virus (HBV) infects chronically over 350 million people globally, and these chronic HBV carriers are at risk of developing cirrhosis and hepatocellular carcinoma.Currently, interfero
Hepatitis B virus X (HBx) protein has been strongly implicated in hepatocarcinogenesis by augmenting HBV pregenome transcription and HBV replication.Estrogen, which exerts its biological function thro
会议