【摘 要】
:
Toxoplsam gondi is an obligate intracellular parasite in warm-blooded animals.It develops ways to inhibit apoptosis, in order to create conditions that benefit for the duplication, simultaneously caus
【机 构】
:
Department of Microbiology and Parasitology, Anhui Medical University, and Provincial Laboratories o
【出 处】
:
中华医学会第六次全国艾滋病、病毒性丙型肝炎暨全国热带病学术会议
论文部分内容阅读
Toxoplsam gondi is an obligate intracellular parasite in warm-blooded animals.It develops ways to inhibit apoptosis, in order to create conditions that benefit for the duplication, simultaneously causing infections duration and dissemination.The host protein quantitative analysis showed that expression profile of host cell proteins changed in the stage of T.gondii infection.As the model of the research of intracellular parasitic protozoan, the mechanism of protein profile change in host cell by T.gondii remains unknown.The miRNA is a cell genome with highly species-specific, which can regulate gene expression through binding of specific mRNA or regulation of protein translation process of mRNA.
其他文献
Objective The aim of this study was to verify whether NK cells were one type of the virus reservoir cells, and to observe whether HIV-1 proviral DNA was still persistent in T lymphocytes and monocytes
目的 确定HIV-1感染者髓样单核细胞中ILT4 mRNA前体的优势剪接异形体,并初探这些优势剪接异形体所编码蛋白质的结构差异和功能分化.方法 利用RT-PCR、PCR、克隆测序及序列分析,对比和分析不同病期及不同进展速度的HIV-1感染者外周血髓单核细胞ILT4 mRNA前体的选择性剪接形式,确定其优势剪接异形体;构建优势剪接异形体的真核表达载体,应用IFA、CLSM、FACS、WB及IP检测和
Objective The present study was aimed to investigate the immunological pathogenesis of Immune Reconstitution Inflammatory Syndrome (IRIS) in acquired immunodeficiency syndrome (AIDS) patients undergoi
Objective To prospectively observe the efficacy, tolerability, immune reconstruction and toxicity of longterm highly antiretroviral therapy (HAART) in HIV-infected Chinese patients.Methods From Februa
第九届国际肾综合征出血热(HFRS)、汉坦病毒肺综合征(HPS)和汉坦病毒学术会议于2013年6月5日~8日在北京举行.本次会议的内容包括HFRS/HPS病原学、流行病学、发病机制、诊断、治疗及预防等多个方面.本文仅简述HFRS和HPS发病机制、治疗和预防方面的主要进展.
Objective To find out which TLRs can be activatied by sporozoite and discuss its effort in development of malaria Liver-Stage.Methods Firstly, we acquired purified sporozoites through DE52 column.Then
目的 探讨危重型恶性疟疾患者的临床特点、救治,并作文献回顾.方法 对我院近年收治的6例危重型恶性疟疾患者的临床特点、实验室检查、治疗预后情况进行描述性总结分析,并复习相关文献,对危重型恶性疟疾的诊治进行探讨.结果 6例患者均为输人性病例,有非洲疫区旅居和工作史,临床表现不典型,多为不规则发热,主要为高热、超高热,且发热持续时间长,缺乏典型的疟疾发作过程,且多出现脑型疟凶险发作的意识障碍表现,伴有急
中医药在治疗麻疹及其并发症方面积累了丰富的临床经验.本文从麻疹的溯源、病因病机、辨证论治、中西医结合治疗及并发症的处理等方面进行了全面阐述.中医在抗击麻疹方面积累了极为丰富的宝贵经验,中西医结合治疗对重症麻疹及其并发症的治疗优势明显,疗效确切.应在充分发挥其优势的同时,进一步加强科学研究,从预防、治疗、后期恢复等多个层面、不同环节积极参与了临床救治和研究,为中医药防治麻疹等重大传染病能力的提升奠定
目的 本研究利用Mkp5-/-C57BL/6小鼠模型探讨了MKP5分子在约氏疟原虫感染中的免疫调控作用.方法 以6-8周雌性Mkp5-/-型C57BL/6小鼠为实验组,野生型C57BL/6小鼠为对照组,经腹腔接种5×106约氏疟原虫致死性虫株P.yoelii17XL感染的红细胞,动态监测和比较生存情况以及原虫密度变化;分别于感染前和早期的不同时间点收集小鼠血清和无菌制备脾细胞悬液,ELISA法检测
Research purpose We want to know the specific mechanism of plasmodium specific CD4 + T cells activation in the whole killed blood stage vaccine.Methods Firstly, C5aactivation in both wild type and C5a