Negative Regulation of TMEM2 in HBV Infection via Activating JAK-STAT Signaling Pathway

来源 :2014年APASL专题会议暨第四届乙型病毒性肝炎专题会议 | 被引量 : 0次 | 上传用户:congrorm
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Background:Transmembrane protein 2(TMEM2) is a single-pass transmembrane protein,and its role in HBV infection remains unclear.Our previous report has shown that its expression is significantly reduced in liver tissues with chronic hepatitis B(CHB),and HepG2.2.15 cells,as compared with healthy liver tissues and HepG2 cells(Hepatology,2012,56:1661-1670).Now we aimed to explore the potential regulation of TMEM2 in HBV infection and its mechanism-related signaling pathway.
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